Why 80% of weaning based NRT fail? Why is it so hard to stop smoking? New answers emerge

“It all started four years ago when a French team of biologists led by Jean-Pol Tassin and Jacques Glowinski (Inserm Unit 114, College of France), announced in the columns of PNAS have taken a major step in understanding Molecular and neurological phenomenon of addiction. It all started, really, when researchers began to analyze what really tobacco (plant!) And discover all the chemical processes that triggered the action of smoking in our brains. We will attempt to “popularize” the revolutionary discoveries and pointed to the Inserm researchers.

Nicotine, an addictive substance

Of course, this data is not compromised. Research has shown, however, that heavy smokers saw their brain less “connected” to nicotine. Probably because too retained in the lungs. The famous peaks are therefore especially nicotine experienced by new smokers or light smokers. Statistics (which unfortunately may well have been commissioned by the tobacco lobby) shows that 80% of weaning tempted by NRT (and other assistance, such as medical or psychological) fail. Why?


Tobacco, nicotine and mechanisms found

The great discovery: dopamine, noradrenaline and serotonin are the three molecules that come into play when you smoke. The recipe is as follows: Tobacco Nicotine + = + dopamine + serotonin norepinephrine = MAOI. What is a MAOI? A powerful antidepressant. It is therefore time to wean only nicotine, or even gesture, but rather to an antidepressant that our brain produces when we smoke, especially when we smoke a lot. We understand immediately the lack of nicotine substitute that product alone, not those MAOI.


They are many, and not all positive.

1. These findings call into question the whole perspective and the theory and practice of tabacologues, which is little appreciated by these specialists.
2. They overthrew a number of ideas, because addiction is much more complex and deep that no one knows. “Stop, this is a matter of will”: how many times the smoker intend this sentence? We are not all equal in front of addiction, let alone deal with mechanisms discovered.
3. They refer to the rank nicotine substitutes crutch fragile that researchers most involved in these discoveries will even qualify placebo.

Unfortunately, these findings, in addition to not give us a solution to stop smoking, paving the way for two terrible consequences and predictable:

1. The tobacco industry in its communication, has always denied that nicotine addiction was the primary reason for smoking. This super-powerful lobby did not need this argument to sell more.
2. If these studies are completed, validated, confirmed, experienced, all candidates will stop find himself on antidepressants? Is it the pharmaceutical lobbies that will make feasted on these findings?

Conclusion halftone

Quitting smoking is possible. We all have examples all around us. These findings have merit exonerate those who are most difficult to stop without giving them solutions.Hopefully the research, conducted through, bring viable solutions, not more harmful than cigarettes.